EVALUATION OF SAFE DOSE, ANTI-DIABETIC ACTIVITY, TOXICOLOGICAL ACTIVITY, & STANDARIZATION OF DIFFERENT EXTRACTS OF Hydnocarpus wightiana (TUVARAKA) SEED, & PREPARED TUVARAKA TAILA

ABSTRACT

Tuvarak Taila is a classical preparation, cited in Susruta Samhita-Chikitsha Sthana. The use in Diabetes is one of many use of that holy preparation. In this current study we are going to perform the Anti-Diabetic activity of Tuvaraka Taila by Pre-Clinical, Clinical & Toxicological study accordingly to establish the safe usage of that product on human as medicine of Diabetes. Here also we are going to perform different laboratory experiments on that, viz. Phytochemical Screening, Thin Layer Chromatographic study, Qualitative & Quantitative Analysis, Microbiological Assay, Limit test for Heavy Metals, Test for Aflatoxin to standardized the test sample. It is said in classical texts that besides Anti-Diabetic activity, this Taila also useful in Leprosy, & if apply externally it can cure certain types of Skin disorders. Now by performing all those experiments we are going to establish the exact safe dose, & its effect on Diabetes referred in classical texts.

Thin Layer Chromatographic study of three different extract of Calendula Officinalis leaves

ABSTRACT

Calendula officinalis is a plant that possess many pharmacological actions like Stomach upset, Ulcer, Menstrual Period Problems, Eye Infections, Inflammation, Wound Healing, Anti-Septic etc. most widely it is used as wound healing purposes. If the leaf of that plant can be applied after crunching at the affected area, blood will be clot within a few time. But while this leaf can perform this action, it means it possess some active compound in it. To find out what the actual component it is, first we have to perform the Thin Layer Chromatographic study. In our present study we are going study the TLC profile of that Calendula officinalis leaf.

ROLE OF MEDICINAL PLANTS IN NON-THERAPEUTIC PURPOSES IN AYURVEDA: A SHORT REVIEW

ABSTRACT

Medicinal plants are the inherent part of Ayurvedic system of medicine. Different forms of plant extract are used in the Ayurvedic treatment regimen. But interestingly the uses of plant either partly or fully in Ayurveda, is not only limited to its direct use in therapeutics, but they are used indirectly in several other places of interest, which are related to pharmaceutical processing and manufacturing of Ayurvedic drugs, or in the application of medicaments to the patients. This interesting short review illuminates the non-therapeutic role of medicinal plants in Ayurveda.

A Review Paper on Psychiatry Disorders & its Treatment by Ayurvedic Approach

ABSTRACT

Psychiatric disorders are astonishingly common. In any given year, over 25 percent of adults have one or more diagnosable mental disorders, according to the National Institute of Mental Health. For the most part, psychiatric disorders are highly responsive to treatment. There have many ayurvedic plants/medicine which are effectively use for the psychiatric disorders. Ayurveda, being a stream of treatment, can no way ignore the importance of psychic condition of a patient to effectively diagnosis and treat disorders. Medical science admits that the root cause of multiple disorders lies in psychic tensions. Ayurveda too has a well developed branch of psychiatry, which has clinically proven practices of treating mental ailments and also physical problems associated with psychological imbalances. On a psychological level we naturally try to harmonies these problems but if we are not able to it can lead to a mental disorders. The causes are many but often stem from our own way of looking at things and the inability or unwillingness of our mind to process what is happening. Sometimes we just don’t want to let go of a belief or viewpoint. At other times we might be attached to a result and when something comes to challenge this, as life tends to do, we find our mind under stress in trying to work through the issue. On an unconscious level the mind may know what to do but at a conscious level the mind wants to do something else creating a conflict between the inner and outer, or the personality and the soul. The result often manifests as a Mental Disorder or sickness.

Prothrombin time test, Phytochemical screening, Thin layer chromatographic study and Quantitative study of Calendula officinalis leaves

ABSTRACT

Calendula officinalis is a plant that possess many pharmacological actions like Stomach upset, Ulcers, Menstural problems, Eye infections, Inflamations, Wound healing, Antiseptics, most widely it is used as if the leaves of that plant rubes on the affected part where the bleeding occurs, it reliefes from pain & immediately stop bleeding. In our current study, we first tried to evaluate out the active ingredients present in that leave that responsible for this action by the help of some phytochemical screening & Thin Layer Chromatographic study. Then we made 2 different extracts of that leave, first with Butanol & the other in water. Then we perform the Prothrombin Time (PT) Test of these two extracts by the help of brain tissue thromboplastin as standard. And after that we also perform the quantitative study on these two extracts of that leave. In the result of PT test we found that when we treated butanol extract with citrated plasma, the coagulation occurs at 4 min 10 sec. when water extract treated with citrated plasma the coagulation occurs at 1 min. & when we treated water extract & citrated plasma with CaCl2 the coagulation occurs at 2 min. After that when we treated the water extract & citrated plasma with brain tissue thromboplastin the coagulation occurs at 20 sec. & then Butanol extract & citrated plasma with brain tissue thromboplastin the coagulation occurs at 2 min. So after performing this study we can come to a conclusion that the water extract of the Calendula officinalis leaves has the more coagulating activity.

POTTALI KALPANA: A CONCISE AND POTENT PHARMACEUTICAL DOSAGE FORM OF INDIAN SYSTEMS OF MEDICINE

ABSTRACT

Indian system of medicine is a treasure of spectacular and peculiar pharmaceutical dosage forms. Ayurvedic herbo-mineral drugs contain several types of formulations with vivid varieties. Maximum potency with minimum dosage is the philosophy of these drugs. Pottali kalpana is one of such, highly potent, concise and embossed dosage form in Ayurveda. The main ingredients of it, is the amalgam of mercury and sulphur, which is treated with different plant materials and ultimately given a compact form by the application of natural binder. This short review describe about the history, necessity, preparation and mode of application of the Pottali kalpana, an unique Ayurvedic pharmaceutical dosage form.

Pharmacological Updates of Pistia Stratiotes (Water Lettuce/ Jalakumbhi): A Mini Review

 ABSTRACT

World is running so first, at this moment medicines have to work to maintain the health of the people to give them power to stabilize them. Modern medicine is working from a decade or so, but many traditional systems of medicines also show some beneficial effects in that era. Likewise Kampo, Traditional Chinese Medicine(TCM), Ayurveda & Herbal Medicines. Those kinds of medicines can give a patient resistant to protect the disease without less side effects. Pistia stratiotes is a plant which plays a commendable role in that era. It is used in different kind of diseases which are described in this mini review.

PHARMACOLOGICAL UPDATES OF PICRORHIZA KURROA

 ABSTRACT

Picrorhiza kurroa is one of the major income generating non-timber forest products found in the Nepalese Himalayas. It is one of the oldest medicinal plants traded from the Karnali zone. Known as Kutki in Nepali, it is a perennial herb and is used as a substitute for Indian gentian. It is also used in different disease conditions. In this mini review article we tried to update the pharmacological research over Picrorhiza Kurroa.

PHYTOCHEMICAL SCRENING OF Calendula officinalis LEAVES

ABSTRACT

Calendula officinalis is a plant which possess many pharmacological actions like Stomach upset, Ulcers, Menstrual Period Problems, Eye Infections, Inflammations, wound Healing, Anti-Septic. most widely it is used as if the leaves of that plant rubes on the affected part where the bleeding is occurred, it relives from pain & it immediately stop bleeding. In all this disease the plant is used as a medicine, but actually the active ingredients present in the leave acts as the reliever, so it is necessary to find out what the molecule is present in that plant. For that the first step is to perform the phytochemical test of that plant. In our present study we perform a phytochemical screening of Calendula officinalis.

A REVIEW ON DIFFERENT PHARMACOLOGICAL IMPORTANCES OF NISHINDA (VITEXNIGUNDO)

ABSTRACT

Ayurvedic plants have shown their effects on various kind of diseases. Those properties of the plants are sublimed in some molecules in the plants, which can be extracted out by performing various kinds of processes (eg. Soxhlation, Percolation). World is running so first, at this moment medicines have to work to maintain the health of the people to give them power to stabilize them. Modern medicine is working from a decade or so, but many traditional systems of medicines also show some beneficial effects in that era. Likewise Kempo, Traditional Chinese Medicine(TCM), Ayurveda & Herbal Medicines. Those kinds of medicines can give a patient resistant to protect the disease without less side effects. Vitexnigundo is a plant which plays a commendable role in that era. It is used in different kind of diseases which are described in this mini review.

Pharmaceutics, ethnopharmacology, chemistry and pharmacology of ayurvedic marine drugs: A review

ABSTRACT

Ayurveda is the ancient thought and treatise that deals with the knowledge of living a healthy life. There are several types of medicaments that are being used in the Ayurvedic mode of treatment. The source of these drugs is diverse and belongs to different category. The category ranges from plants and animals to minerals, and encircles around different types of species of plants and animals with vivid habitats. In the course of last thirty years, marine organisms have been proven to be a rich source of wide range of worthy compounds for medicine. In Ayurveda there is a wide range of marine drugs like Mukta, Varatika, Praval, Agnijvar, Samudra phena, etc that are useful in the management of numerous diseases like paralysis, hyperacidity, cancer, dyspepsia, eye diseases, etc. This review makes a humble effort to summarize and gather knowledge about different types of marine drugs that are described and explained in Ayurvedic system of medicine, its traditional processing and chemistry, ethno pharmacology and pharmacological role.

METHOD DEVELOPMENT FOR ESTIMATION OF PIPERINE IN POLYHERBAL LOZENGES BY UV SPECTROSCOPIC METHOD.

ABSTRACT

Polyherbal lozenges are immensely popular in today’s world, due to its highly palatable taste, cheap rate, soothing effect, counter-irritant effect, decreasing abdominal flatulence, and for treatment of anorexia. Herbs of Piper species are one of the most important ingredients of polyherbal lozenges and Piperine is the main chemical constituent of Piper species. In the present study an attempt was made for the estimation of piperine in ayurvedic lozenges sample by using UV-spectrophotometer. Three samples of lozenges from different brands have been selected for this purpose. The amount of piperine in each lozenge of all the three samples (S-1, S-2, and S-3) was found to be 3.1 μg, 2.7 μg and 2.8 μg respectively. Recovery studies were carried out by standard addition method and the average % recovery of the three samples S-1, S-2, S-3 were found to be 98.62%, 99.32%, and 98.35% respectively.

Hydration-dehydration treatments for the maintenance of germinability and better seedling emergence of fresh and old Basil (Ocimum sanctumL.) seed

ABSTRACT

Hydration-dehydration treatments in two months (medium vigour) and seven months (medium to low vigour) old basil(Ocimumsnactum L.) seedswere given for the improvement of storability and field emergenceafter subsequent storage. Hydration-dehydration treatments were given with distilled water and different solutions (ascorbic acid - 100ppm & 250 ppm, KNO3- 100ppm & 250 ppm, Acetyl salicylic acid – 100ppm & 250 ppm and para-Amino benzoic acid (PABA) – 100 ppm & 250 ppm). Few treatments were significantlyeffective over control for the maintenance of seed germinability and field emergence. Particularly basil seed hydration – dehydration with ascorbic acid - 100ppm,KNO3- 250 ppm and acetyl salicylic acid - 100ppm solutions showed very effective results for the maintenance of vigour and viability of basil seed.

Pharmacological Properties of Aegle Marmelos: A Mini Review

ABSTRACT 

Ayurvedic plants have shown their effects on various kind of diseases. Those properties of the plants are sublimed in some molecules in the plants, which can be extracted out by performing various kind of processes (eg. Soxhlation, Percolation). Many plants which are used by the human being in daily life, also have some effects in curing some disease conditions. Likewise in our current review Aegle marmelos (Beal) have Antidiarrhoeal, Antidiabetic activities etc. Many Pharmacological Activities have been revealed & organized in this review article, but there have a wide scope of research to perform on this plant.