ABSTRACT
Indian system of medicine is a treasure of spectacular and peculiar pharmaceutical dosage forms. Ayurvedic herbo-mineral drugs contain several types of formulations with vivid varieties. Maximum potency with minimum dosage is the philosophy of these drugs. Pottali kalpana is one of such, highly potent, concise and embossed dosage form in Ayurveda. The main ingredients of it, is the amalgam of mercury and sulphur, which is treated with different plant materials and ultimately given a compact form by the application of natural binder. This short review describe about the history, necessity, preparation and mode of application of the Pottali kalpana, an unique Ayurvedic pharmaceutical dosage form.
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